Sounds like the whole "co-host" illusion needs to end.
She is providing the space, but she has no business playing any role in running the poker game.
You are the host of the poker game, and this puts you in a really awkward situation because the attendees—including the space-provider—are an assortment of completely non-serious players who think it's appropriate to engage in this sort of behavior.
Approach #1: Make an announcement at the start of next game that you're sorry you haven't been firm enough about this, but that people need to stop commenting on board texture, suggesting people are bluffing, or otherwise improperly influencing players. This is a standard rule in every place where poker is played for money. It's unfair to the players still in the hand. OPTAH, as they say. Best of luck.
Approach #2: If approach #1 is met with snark and whinging, start sharing all your experienced-poker-player takes on everyone else's hands when they're trying to play. Describe every change in board texture. Call out apparent bluffs. Explain why a bet looks strong. Note that the player who just reraised preflop hasn't reraised preflop for 3 sessions in a row. Be as totally insufferable as they're being. Show them what's wrong about this.
(Just kidding, don't do #2. But man, it's tempting.)
Approach #3: Stop hosting this game. I don't know how long you've been hosting this, but if you're a fairly serious player/host for whom it's important for a game to operate soundly and according to reasonable, consistent rules, this may never quite work out. Sounds like you have a game full of party animals who love drinking and shouting, and strict rules are about as important to them in poker as they would be in Cards Against Humanity.
Hell, maybe you could host games of CAH instead. It's a better match for people like this.
