All the meta factors are what make poker so complex and fun.
@gkitt80 if you are playing at a casino with a bunch of unknowns then don't worry about balancing your 3 betting range. If I sit down at a 1/2 game whether its at my local casino or Vegas I am playing tight and never raising trash like K3 or K4. Simply play ABC poker and raise the hands you should and fold all else. There are too many bad players that will call your preflop bet and keep calling with middle pair not knowing better.
If we are against bad players that will call you all the way down my initial squeeze play will backfire. If people are bad call stations then the strategy is to play tight, hit a hand, and take them to value town. Most money made at low stakes NLHE is by taking people to value town not by doing fancy squeeze plays.