I was thinking about this a bit more this morning. Some players who have never played online before and play a loose, random sort of home game style will probably suffer the most. Specifically, I was thinking about flops seen percent (roughly the closest thing to VPIP stat you will find in poker mavens). I tend to be kind of nitty. Especially when it comes to pre-flop hand selection. Not a total nit, but my UTG raising range would be 98s and up for suited connectors, KQ, AQ, AK maybe QJ, and 55 and up for pairs. Anyway, I looked at my flops seen % during a game the other night and it was 38% I am usually somewhere between 31 and 44% typically. I asked one of our home game regs who is very loose in his pre-flop hand selection and his flops seen was 70% Maintaining preflop discipline may be easier online.
Hands come by so much faster that I don't struggle with the patience required to maintain my preflop discipline. For the loose folks who just have to give any two cards a spin, they are going to be playing so many hands that they are going to be limp folding so many times that they will be constantly leaking chips at a high rate.
In a home game where hands can take forever as people stop dealing to chat, or shuffle slowly, etc, etc, it can get hard to resist the temptation to play crap cards out of position because you are bored out of your brain and just want to play. Online fits my preflop strategy so much better. Fold? No biggie, another hand will start in very short time. Bored? I can watch the action without distracting conversations or even browse the web in the background.